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Myo-Inositol Plus
Myo-Inositol Plus
Myo-Inositol Plus
Myo-Inositol Plus
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Myo-Inositol Plus

$31.16
$38.95 $31.16

Myo-Inositol Plus is a daily formula designed to support healthy ovulation, balanced androgen levels, and insulin sensitivity using clinically studied inositols and targeted micronutrients so you can feel more steady, supported, and in sync with your cycle.
Supports menstrual regularity, ovarian function, and metabolic health.

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Myo-Inositol Plus

Myo-Inositol Plus

$31.16
$38.95 $31.16

Free delivery on orders over $99

Key highlights
  • Supports healthy menstrual cycle regularity
  • Supports ovarian function and ovulation
  • Supports healthy insulin sensitivity
  • Supports balanced androgen levels
  • Supports metabolic and cardiometabolic health

How to use

Serving size: 4 capsules
Servings per container: 30

Suggested use: Take 4 capsules daily with food and water. For best results, split into 2 capsules in the morning and 2 capsules in the evening.

Optional routine:

  • Start with 2 capsules daily for 3–5 days, then increase to the full serving.
  • Take with meals to support digestive comfort.

Ingredients

Key ingredients:

  • Myo-inositol
  • D-chiro-inositol (40:1 ratio)
  • Vitamin D3
  • Chromium (picolinate)
  • Zinc (citrate)
  • Spearmint leaf
  • Fenugreek seed extract
  • Green tea leaf extract

Want full details? Scroll down for the full Supplement Facts panel, ingredient-by-ingredient breakdown, and research links.

Other ingredients: Hypromellose (capsule), rice flour, L-leucine, rice hull concentrate.

Shipping & returns

If you’re looking to return or exchange your order for whatever reason, we're here to help! We offer free returns within 30 days of purchase.

You can return your product for store credit, a different product, or a refund to the original payment method.
Myo-Inositol Plus
Myo-Inositol Plus
Myo-Inositol Plus
Myo-Inositol Plus
Myo-Inositol Plus
Myo-Inositol Plus

Why you'll love it

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Clinically Aligned Formulation

Formulated with a 40:1 myo-inositol to D-chiro-inositol ratio used in clinical research, plus carefully selected cofactors to support hormone and metabolic health. Third-party tested for quality and purity.

Support Where It Matters Most

Designed to support cycle regularity, ovulatory function, and steady energy through balanced insulin and androgen pathways. Built for women who want foundational hormone support without harsh formulas.

Easy to Make It a Habit

Four capsules daily. Easy to split morning and evening. Stack with your foundational multivitamin or prenatal and subscribe to stay consistent month after month.

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Click to view the full table

Supplement Facts
Serving Size: 4 Capsules
Servings Per Container: 30

(Insert Supplement Facts image: )

Active ingredients per serving:

  • Vitamin D (as cholecalciferol) – 25 mcg (1,000 IU)
  • Vitamin B6 (as pyridoxal-5-phosphate) – 8.5 mg
  • Zinc (as zinc citrate) – 5.5 mg
  • Chromium (as chromium picolinate) – 100 mcg
  • Inositol – 2,000 mg
  • Fenugreek seed extract – 250 mg
  • Spearmint leaf – 100 mg
  • Nettle root extract – 100 mg
  • Green tea leaf extract – 100 mg
  • D-Chiro-inositol (from carob pods) – 50 mg

Other ingredients: Hypromellose, rice flour, L-leucine, rice hull concentrate.

Key Ingredients

Myo-Inositol (2,000 mg)

Supports ovulation and insulin sensitivity.

Learn More

Myo-Inositol (2,000 mg)

Myo-inositol is a naturally occurring compound involved in insulin signaling and ovarian function. Clinical studies in women with PCOS have shown that myo-inositol supports healthier insulin response and promotes more regular ovulation and menstrual cycles. It has also been studied for supporting oocyte quality in women undergoing fertility support. It is the foundation of this formula to target the metabolic and hormonal pathways most central to cycle balance.

D-Chiro-Inositol (50 mg, 40:1 ratio)

 Complements myo-inositol for balanced hormone signaling.

Learn More

D-Chiro-Inositol (50 mg, 40:1 ratio)

D-chiro-inositol is another form of inositol involved in glucose metabolism and ovarian signaling. Research suggests that a 40:1 myo- to D-chiro-inositol ratio mirrors physiological balance and supports healthy ovarian response. Excess D-chiro alone may not support optimal ovarian outcomes, making the ratio important. This formula uses a research-aligned ratio to complement myo-inositol’s effects.

Chromium (as chromium picolinate)

Supports healthy blood sugar metabolism.

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Chromium (as chromium picolinate)

Chromium is a trace mineral that enhances insulin receptor activity. Clinical trials in women with PCOS show improvements in insulin sensitivity and select metabolic markers with chromium supplementation. Improved insulin function can positively influence androgen balance and ovulatory patterns. It is included as a supportive cofactor to reinforce insulin-targeted pathways.

Spearmint Leaf

Supports balanced androgen levels.

Learn More

Spearmint Leaf

Spearmint is a botanical studied for its influence on androgen activity. Clinical trials in women with PCOS have demonstrated reductions in free and total testosterone with spearmint intake. Healthier androgen balance can support clearer skin and reduced excess hair growth over time. It is included to provide plant-based support for androgen pathways.

Fenugreek Seed Extract

Supports ovarian and metabolic health.

Learn More

Fenugreek Seed Extract

Fenugreek is traditionally used to support glucose metabolism. In clinical research involving women with PCOS, fenugreek extract has been associated with improvements in menstrual cyclicity and ovarian morphology when used alongside other metabolic interventions. Balanced glucose metabolism is central to hormone regulation. It is included as an adjunctive botanical for cycle and metabolic support.

Green Tea Leaf Extract

 Supports metabolic and antioxidant health.

Learn More

Green Tea Leaf Extract

Green tea contains catechins that support antioxidant balance and metabolic function. Clinical trials in women with PCOS show modest improvements in weight, insulin markers, and androgen levels with supplementation. Antioxidant support may also benefit ovarian environment and cardiometabolic health. It is included to complement the metabolic focus of the formula.

See More Ingredients
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Why Dr. Brighten Recommends It

Many women struggle with irregular cycles, stubborn symptoms, and metabolic shifts that leave them feeling out of sync. Supporting insulin sensitivity and ovarian signaling is often the missing piece in restoring rhythm and balance.

I formulated Myo-Inositol Plus around three priorities:

  1. Support insulin sensitivity as a root driver of hormone imbalance
  2. Support ovulation and ovarian function
  3. Support balanced androgen activity and metabolic health

I recommend Myo-Inositol Plus for women who want support with irregular cycles, signs of androgen excess, and metabolic shifts, especially during high-stress seasons or when trying to optimize cycle regularity.

Ask a clinician first if you are pregnant, nursing, trying to conceive, taking medications, or managing a medical condition.

Research Shows

What the Research Shows: Clinical Evidence Summary

Myo-Inositol Plus provides myo-inositol and D-chiro-inositol in a 40:1 physiological ratio, with synergistic cofactors at doses contributing to ovarian function, insulin sensitivity, hormone balance, and metabolic health support. Note: Individual ingredient RCTs typically evaluate single agents at higher doses than in multi-ingredient formulas.

*These studies explore outcomes related to individual ingredients used in Myo-Inositol Plus. Research on individual ingredients does not necessarily reflect the effect of the full formula. When study doses differ from Myo-Inositol Plus, we note it. Not intended to diagnose, treat, cure, or prevent any disease.

Myo-Inositol (2,000 mg/day)
 Studied for: improvements in insulin resistance, ovulation/menstrual regularity, oocyte quality, androgen levels, and IVF outcomes in women with PCOS (multiple RCTs and meta-analyses).pmc.ncbi.nlm.nih+2
Dose note: RCTs typically 2–4 g/day. Formula: 2 g/day. (PMC)
Further reading:
Unfer et al., 2017 meta-analysis (9 RCTs): PMC
 Gerli et al., 2007 RCT (ovarian function): PubMed
 Costantino et al., 2016 IVF RCT: Wiley
 Fitzgerald et al., 2023 meta-analysis (26 RCTs): PMC

D-Chiro-Inositol (50 mg/day)
 Studied for: enhanced metabolic and ovarian response when combined with myo-inositol in 40:1 ratio for PCOS and IVF (RCTs); high DCI doses alone may impair oocyte quality.egoipcos+1
Dose note: Studies use 20–50 mg/day DCI with 800–2,000 mg MI. Formula: 50 mg/day with 2 g MI. (EGOI-PCOS PDF)
Further reading:
Nordio & Proietti, 2012 RCT (MI+DCI): PubMed
 DCI oocyte quality review: [IJMDAT PDF](https://www.ijmdat.com/wp-content/uploads/sites/3/2019/12/e208-A-double-edge-sword-the-role-of-D-chiro-inositol-in-oocyte-and-em ...)

Vitamin D3 (25 mcg/1,000 IU/day)
 Studied for: reductions in insulin resistance, HOMA-IR, and menstrual irregularity in vitamin D-deficient PCOS women (RCTs and meta-analyses).pmc.ncbi.nlm.nih+2
Dose note: Studies use 1,000–4,000 IU/day. Formula: 1,000 IU/day. (PMC)
Further reading:
Tabrizi et al., 2019 RCT: PMC
 Vitamin D PCOS review: PMC

Vitamin B6 as P5P (8.5 mg/day)
 Studied for: cofactor support for neurotransmitter synthesis and steroid hormone metabolism; B-complex RCTs show mood/stress benefits in related populations.[egoipcos]​
Further reading:
Systematic review on B vitamins: MDPI

Zinc (as citrate, 5.5 mg/day)
 Studied for: improvements in insulin sensitivity, fasting glucose/insulin, and triglycerides in PCOS women (RCT).[pubmed.ncbi.nlm.nih]​
Dose note: RCT used 50 mg elemental zinc. Formula: 5.5 mg/day. (PubMed)
Further reading:
Jamilian et al., 2015 RCT: PubMed

Chromium (as picolinate, 100 mcg/day)
 Studied for: reductions in BMI, insulin resistance, and improved ovulation/menstrual regularity in PCOS (multiple RCTs).unboundmedicine+2
Dose note: Studies use 200–1,000 mcg/day. Formula: 100 mcg/day. (PubMed)
Further reading:
Lucidi et al., 2015 RCT: PubMed
 Jamilian et al., 2018 RCT (IVF candidates): Frontiers

Fenugreek Seed Extract (250 mg/day)
 Studied for: improvements in ovarian morphology and menstrual cyclicity when added to metformin in oligo-ovulatory PCOS (RCT).[pmc.ncbi.nlm.nih]​
Dose note: RCT used 1,000 mg/day. Formula: 250 mg/day. (PMC)
Further reading:
Neelakantan et al., 2012 RCT: PMC

Spearmint Leaf (100 mg/day)
 Studied for: reductions in free/total testosterone and improved hirsutism scores in PCOS women (RCT).onlinelibrary.wiley+1
Dose note: RCT used spearmint tea equivalent (~2 cups/day). Formula: 100 mg/day. (Wiley)
Further reading:
Grant, 2010 RCT: Wiley

Green Tea Leaf Extract (100 mg/day)
 Studied for: reductions in BMI, weight, insulin, and free testosterone in overweight PCOS women (RCTs).pmc.ncbi.nlm.nih+1
Dose note: Studies use 1,000 mg/day. Formula: 100 mg/day. (PMC)
Further reading:
Fathizadeh et al., 2017 RCT: PMC

Nettle Root Extract (100 mg/day) Studied for: lignans that bind SHBG and modulate androgen bioavailability (in vitro and mechanistic studies; limited PCOS data).thieme-connect+2 Further reading: EMA assessment report: [EMA](https://www.ema.europa.eu/en/documents/herbal-report/final-assessment-report-urtica-dioica-l-urtica-urens-l-radix-revision-1_en. ...) Schöttner et al., 1997: PubMed

30-Day Guarantee

Try Myo-Inositol Plus for 30 days. If it’s not for you, contact our team for help with next steps.

FAQ

How long does one bottle last?

One bottle lasts 30 days when taken at the full serving of 4 capsules daily.

When should I take it?

Take with food. Many women prefer splitting between morning and evening meals. Can I take it every day?

Yes. This formula is designed for daily use and consistency supports best results.

Can I take it with other supplements?

Yes, it pairs well with a multivitamin, prenatal, or omega-3. If taking medications, consult your clinician.

Is this safe if I am trying to conceive?

Inositol has been studied in women optimizing ovulatory health. Speak with your healthcare provider for personalized guidance.

What if I have a sensitive stomach?

Start with 2 capsules daily for several days, then increase to the full serving with meals.

Who is this not for?

Not intended for children. Consult your clinician if pregnant, nursing, taking medications, or managing a medical condition.

Pairs well with

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