Women’s Probiotic delivers a 14 billion CFU proprietary blend of clinically researched strains (Bacillus clausii SC109™, Bacillus subtilis HU58™, Bacillus coagulans SC208™, Lactobacillus acidophilus La-14®, Lactobacillus rhamnosus HN001™), plus aronia berry polyphenols (200 mg) and partially hydrolyzed guar gum prebiotic fiber (500 mg). Note: Individual ingredient RCTs typically evaluate strains or ingredients alone or in different combinations at varied doses.
*These studies explore outcomes related to individual ingredients used in Women’s Probiotic. Research on individual ingredients does not necessarily reflect the effect of the full formula. When study doses differ from Women’s Probiotic, we note it. Not intended to diagnose, treat, cure, or prevent any disease.
HOWARU Feminine Health Blend (Lactobacillus rhamnosus HN001™ + L. acidophilus La-14®)
Studied for: vaginal Lactobacillus colonization after oral intake, improvements in Nugent scores and symptoms in intermediate vaginal microbiota, and reduced recurrence of bacterial vaginosis (BV) and recurrent vulvovaginal candidiasis (RVVC) when used as adjuvant/maintenance after standard therapy (multiple RCTs).nutrition-evidence+5
Dose note: RCTs used Respecta® complex (these strains + lactoferrin) at ~10^9 CFU/strain/day; formula delivers equivalent strains (CFU undisclosed per strain). (PubMed)
Further reading:
De Alberti et al., 2015 (RCT pilot, healthy women): Springer
Russo et al., 2019 BV prevention RCT: PubMed
Russo et al., 2019 RVVC maintenance RCT: Wiley
Russo et al., 2018 intermediate microbiota RCT: PubMed
Lactobacillus rhamnosus HN001™ (standalone)
Studied for: reduced gestational diabetes risk, improved fasting glucose, and lower postpartum depression/anxiety scores in pregnant/at-risk women (RCTs).vidm+2
Dose note: RCTs used 6 × 10^9 CFU/day; formula dose undisclosed. (PMC)
Further reading:
Wickens et al., 2017 GDM RCT: PMC
Sivakumaran et al., 2017 postpartum mood RCT: PubMed
MegaTrio™ Bacillus Blend (B. subtilis HU58™, B. coagulans SC208™, B. clausii SC109™)
Studied for: reductions in serum IL-6 (~45%) and TNF-α (~55%) in healthy adults (HU58 open-label trial); supported gut barrier function, microbial diversity, and lowered inflammatory cytokines during antibiotic-induced dysbiosis (HU58/SC208 SHIME® model).journals.indexcopernicus+5
Dose note: Human trial 2 × 10^9 CFU HU58/day (open-label); SHIME® model equivalent. Formula: 14 billion CFU total blend. (Indian Practitioner)
Further reading:
Dound et al., 2019 HU58 immune trial: Index Copernicus
Marzorati et al., 2020 SHIME® model: PMC
Aronia Berry Juice Powder (200 mg)
Studied for: improved endothelial function (flow-mediated dilation) and favorable gut microbiota shifts (e.g., Anaerostipes, Bacteroides) in healthy adults (RCT).kclpure.kcl.ac+1
Dose note: RCT used 116 mg polyphenols (extract) or 12 mg (whole fruit); formula 200 mg powder. (PubMed)
Further reading:
Istas et al., 2019 RCT: AJCN
Systematic review (2025): NAJNR
Partially Hydrolyzed Guar Gum (PHGG / SunFiber®, 500 mg) Studied for: improved stool form, increased Bifidobacterium abundance, and shifted microbiota toward beneficial taxa (e.g., Akkermansia) in healthy adults (RCTs).experts.umn+4 Dose note: RCTs 5–6 g/day; formula 500 mg/day. (PMC) Further reading: Yasukawa et al., 2019 RCT: PubMed
Minekus et al., 2020 athlete RCT: PMC